Chemical stability, enzymatic hydrolysis, and nasal uptake of amino acid ester prodrugs of acyclovir

2001 ◽  
Vol 90 (5) ◽  
pp. 615 ◽  
Author(s):  
Chun Yang ◽  
Hongwu Gao ◽  
Ashim K. Mitra
Keyword(s):  
Amino Acid ◽  
Enzymatic Hydrolysis ◽  
Chemical Stability ◽  
Acid Ester ◽  
Amino Acid Ester ◽  
Ester Prodrugs

Amino Acid Ester Prodrugs of the Anticancer Agent Gemcitabine:  Synthesis, Bioconversion, Metabolic Bioevasion, and hPEPT1-Mediated Transport

2005 ◽  
Vol 2 (2) ◽  
pp. 157-167 ◽  
Author(s):  
Xueqin Song ◽  
Philip L. Lorenzi ◽  
Christopher P. Landowski ◽  
Balvinder S. Vig ◽  
John M. Hilfinger ◽  
...  
Keyword(s):  
Amino Acid ◽  
Acid Ester ◽  
Anticancer Agent ◽  
Amino Acid Ester ◽  
Ester Prodrugs

Synthesis of Stavudine Amino Acid Ester Prodrugs with Broad-Spectrum Chemotherapeutic Properties for the Effective Treatment of HIV/AIDS.

ChemInform ◽  
2004 ◽  
Vol 35 (26) ◽  
Author(s):  
Dharmarajan Sriram ◽  
Perumal Yogeeswari ◽  
Narasimharaghavan Srichakravarthy ◽  
Tanushree Ratan Bal
Keyword(s):  
Amino Acid ◽  
Effective Treatment ◽  
Broad Spectrum ◽  
Acid Ester ◽  
Amino Acid Ester ◽  
Ester Prodrugs ◽  
Hiv Aids

Amino Acid Ester Prodrugs of the Antiviral Agent 2-Bromo-5,6-dichloro-1-(β-d-ribofuranosyl)benzimidazole as Potential Substrates of hPEPT1 Transporter

2005 ◽  
Vol 48 (4) ◽  
pp. 1274-1277 ◽  
Author(s):  
Xueqin Song ◽  
Balvinder S. Vig ◽  
Philip L. Lorenzi ◽  
John C. Drach ◽  
Leroy B. Townsend ◽  
...  
Keyword(s):  
Amino Acid ◽  
Acid Ester ◽  
Antiviral Agent ◽  
Amino Acid Ester ◽  
Ester Prodrugs

scholarly journals Floxuridine Amino Acid Ester Prodrugs: Enhancing Caco-2 Permeability and Resistance to Glycosidic Bond Metabolism

2005 ◽  
Vol 22 (9) ◽  
pp. 1510-1518 ◽  
Author(s):  
Christopher P. Landowski ◽  
Xueqin Song ◽  
Philip L. Lorenzi ◽  
John M. Hilfinger ◽  
Gordon L. Amidon
Keyword(s):  
Amino Acid ◽  
Acid Ester ◽  
Amino Acid Ester ◽  
Glycosidic Bond ◽  
Ester Prodrugs

scholarly journals Kinetics and Mechanisms of Activation of α-Amino Acid Ester Prodrugs of Camptothecins

2006 ◽  
Vol 49 (14) ◽  
pp. 4344-4355 ◽  
Author(s):  
Lin Song ◽  
Robert Bevins ◽  
Bradley D. Anderson
Keyword(s):  
Amino Acid ◽  
Acid Ester ◽  
Amino Acid Ester ◽  
Ester Prodrugs

scholarly journals 5′-O-Aliphatic and amino acid ester prodrugs of (−)-β-d-(2R,4R)-dioxolane-thymine (DOT): Synthesis, anti-HIV activity, cytotoxicity and stability studies

2009 ◽  
Vol 17 (3) ◽  
pp. 1404-1409 ◽  
Author(s):  
Yuzeng Liang ◽  
Ashoke Sharon ◽  
Jason P. Grier ◽  
Kimberly L. Rapp ◽  
Raymond F. Schinazi ◽  
...  
Keyword(s):  
Amino Acid ◽  
Acid Ester ◽  
Amino Acid Ester ◽  
Stability Studies ◽  
Anti Hiv ◽  
Ester Prodrugs
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